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What Are the Special Risks for Nitrite Abusers?

From National Institute on Drug Abuse, for About.com

Updated: November 21, 2007

About.com Health's Disease and Condition content is reviewed by Steven Gans, MD

Question: What Are the Special Risks for Nitrite Abusers?

Answer: Nitrites are abused mainly by older adolescents and adults. Typically, individuals who abuse nitrites are seeking to enhance sexual function and pleasure. Research shows that abuse of these drugs in this context is associated with unsafe sexual practices that greatly increase the risk of contracting and spreading such infectious diseases as HIV/AIDS and hepatitis.

Recent animal research raises the possibility that there may be a link between abuse of nitrite inhalants and the development and progression of infectious diseases and tumors. The research indicates that inhaling nitrites depletes many cells in the immune system and impairs immune system mechanisms that fight infectious diseases.

A recent study found that even a relatively small number of exposures to butyl nitrite can produce dramatic increases in tumor incidence and growth rates in animals.

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